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Asbestos Mesothelioma Cancer Clinical Trials

The US Government keeps an online database, at clinicaltrials.gov, of clinical research studies for Mesothelioma cancer, but doesn't review or approve the safety and science of these trials. The website is maintained by the National Library of Medicine (NLM). The links below go to the clinical trial information on clinicaltrials.gov. Talk with your health care professional about possible risks and benefits before joining any studies.

Evaluating Ivonescimab As a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Fri, 21 Feb 2025 00:00:00 EST

Conditions: Pleural Mesotheliomas
Interventions: Drug: Ivonescimab
Sponsors: Intergroupe Francophone de Cancerologie Thoracique; Summit Therapeutics
Not yet recruiting

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

Fri, 21 Feb 2025 00:00:00 EST

Conditions: Mesothelioma; Malignant Mesothelioma (MM); Early-stage Mesothelioma; Subclinical Mesothelioma; BRCA1-Associated Protein-1 (BAP1) Mutations; Early-stage BAP1-associated Malignancies
Interventions: Drug: alrizomadlin
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

A Study of SGN-MesoC2 in Advanced Solid Tumors

Fri, 21 Feb 2025 00:00:00 EST

Conditions: Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Pancreatic Adenocarcinoma; Colorectal Neoplasms; Mesothelioma; Other Solid Tumors; Endometrial
Interventions: Drug: PF-08052666
Sponsors: Seagen Inc.
Recruiting

SW-682 in Advanced Solid Tumors

Wed, 12 Feb 2025 00:00:00 EST

Conditions: Advanced Solid Tumor; Mesothelioma, Malignant
Interventions: Drug: SW-682; Drug: Combination Therapy
Sponsors: SpringWorks Therapeutics, Inc.
Recruiting

Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study)

Tue, 11 Feb 2025 00:00:00 EST

Conditions: Pleural Mesothelioma
Interventions: Drug: Carboplatin/Cisplatin - Pemetrexed - Pembrolizumab
Sponsors: Istituto Oncologico Veneto IRCCS; MSD Italia S.r.l.
Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

Tue, 18 Feb 2025 00:00:00 EST

Conditions: Unresectable Pleural Mesothelioma
Interventions: Drug: Volrustomig; Drug: Pemetrexed; Drug: Carboplatin; Drug: Cisplatin; Drug: Nivolumab; Drug: Ipilimumab
Sponsors: AstraZeneca
Recruiting

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Fri, 14 Feb 2025 00:00:00 EST

Conditions: Locally Advanced Solid Tumor
Interventions: Drug: TNG462; Drug: Pembrolizumab
Sponsors: Tango Therapeutics, Inc.
Recruiting

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Wed, 19 Feb 2025 00:00:00 EST

Conditions: Cutaneous Melanoma; Non-small Cell Lung Cancer; Colorectal Neoplasms; Pancreatic Neoplasms; Mesothelioma
Interventions: Drug: PF-08046049
Sponsors: Seagen, a wholly owned subsidiary of Pfizer
Recruiting

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Mon, 17 Feb 2025 00:00:00 EST

Conditions: Peritoneal Malignant Mesothelioma
Interventions: Biological: Atezolizumab; Biological: Bevacizumab; Procedure: Biospecimen Collection; Drug: Carboplatin; Procedure: Computed Tomography; Procedure: Cytoreductive Surgery; Drug: Hyperthermic Intraperitoneal Chemotherapy; Drug: Pemetrexed; Procedure: Positron Emission Tomography
Sponsors: National Cancer Institute (NCI)
Recruiting

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Wed, 19 Feb 2025 00:00:00 EST

Conditions: All Malignancies; Advanced Malignancies; Hematologic Malignancy; Solid Tumor; Follicular Lymphoma (FL); Non-Hodgkin Lymphoma (NHL); Diffuse Large B-Cell Lymphoma (DLBCL); Epithelioid Sarcoma (ES); Synovial Sarcoma; Renal Medullary Carcinoma; Mesothelioma; Rhabdoid Tumor
Interventions: Drug: Tazemetostat; Drug: Itraconazole; Drug: Tazemetostat; Drug: Rifampin
Sponsors: Epizyme, Inc.
Completed