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Asbestos Mesothelioma Cancer Clinical Trials

The US Government keeps an online database, at clinicaltrials.gov, of clinical research studies for Mesothelioma cancer, but doesn't review or approve the safety and science of these trials. The website is maintained by the National Library of Medicine (NLM). The links below go to the clinical trial information on clinicaltrials.gov. Talk with your health care professional about possible risks and benefits before joining any studies.

First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.

Sun, 27 Apr 2025 00:00:00 EDT

Conditions: Suspected Malignant Lung Neoplasm; Pleural Effusion; Pleural Effusion, Malignant; Mesothelioma, Malignant
Interventions: Procedure: Local Anesthesia Thoracoscopy; Device: Pleuroscopy with Rigid Thoracoscope and Forceps biopsies
Sponsors: National and Kapodistrian University of Athens; Sotiria Thoracic Diseases Hospital of Athens
Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Tue, 22 Apr 2025 00:00:00 EDT

Conditions: Mesothelioma; Non Small Cell Lung Cancer; Malignant Peripheral Nerve Sheath Tumors; Solid Tumor; Pancreatic Adenocarcinoma; Advanced Solid Tumor
Interventions: Drug: MRTX1719
Sponsors: Bristol-Myers Squibb
Recruiting

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

Sun, 27 Apr 2025 00:00:00 EDT

Conditions: Mesothelioma; Malignant Mesothelioma (MM); Early-stage Mesothelioma; Subclinical Mesothelioma; BRCA1-Associated Protein-1 (BAP1) Mutations; Early-stage BAP1-associated Malignancies
Interventions: Drug: alrizomadlin
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

Using CICS-1 and SPM-011 and [18F]FBPA Commissioned by CICS and Sumitomo Heavy Industries and STELLA PHARMA

Tue, 15 Apr 2025 00:00:00 EDT

Conditions: Thoracic Solid Malignant Tumor
Interventions: Radiation: BNCT; Diagnostic Test: [18F]FBPA
Sponsors: Stella Pharma Corporation; Cancer Intelligence Care Systems, Inc.; Sumitomo Heavy Industries, Ltd.
Enrolling by invitation

A Study of SGN-MesoC2 in Advanced Solid Tumors

Sun, 20 Apr 2025 00:00:00 EDT

Conditions: Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Pancreatic Adenocarcinoma; Colorectal Neoplasms; Mesothelioma; Other Solid Tumors; Endometrial
Interventions: Drug: PF-08052666
Sponsors: Seagen, a wholly owned subsidiary of Pfizer
Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

Thu, 24 Apr 2025 00:00:00 EDT

Conditions: Unresectable Pleural Mesothelioma
Interventions: Drug: Volrustomig; Drug: Pemetrexed; Drug: Carboplatin; Drug: Cisplatin; Drug: Nivolumab; Drug: Ipilimumab
Sponsors: AstraZeneca
Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Sun, 20 Apr 2025 00:00:00 EDT

Conditions: Advanced Renal Cell Carcinoma; Advanced Mesothelioma; Advanced Osteosarcoma
Interventions: Drug: CAR.70/IL15-transduced CB-derived NK cells; Drug: Fludarabine phosphate; Drug: Cyclophosphamide
Sponsors: M.D. Anderson Cancer Center
Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Sun, 20 Apr 2025 00:00:00 EDT

Conditions: High Grade Epithelial Ovarian Cancer; High Grade Serous Ovarian Cancer; Primary Peritoneal Carcinoma; Fallopian Tube Cancer; Endometrial Cancer; Non-small Cell Lung Cancer; Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC); Mesothelioma; Breast Adenocarcinoma; Triple Negative Breast Cancer; Hormone Receptor-positive/Her2 Negative Breast Cancer; Platinum-resistant Ovarian Cancer (PROC); Platinum Sensitive Ovarian Cancer (PSOC); Primary Refractory Ovarian Cancer; Uterine Cancer
Interventions: Drug: Rina-S; Drug: Carboplatin; Drug: Bevacizumab; Drug: Pembrolizumab
Sponsors: Genmab
Recruiting

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Sun, 20 Apr 2025 00:00:00 EDT

Conditions: Microsatellite High Cancers; Peritoneal Mesothelioma; Extrapulmonary High Grade; Neuroendocrine Carcinomas; Cervical Carcinoma; Hodgkin's Lymphoma; Pleural Mesothelioma; Small Cell Lung Cancer
Interventions: Drug: XmAb20717
Sponsors: M.D. Anderson Cancer Center
Suspended

dENdritic Cell Therapy Combined With SURgEry in Mesothelioma

Fri, 25 Apr 2025 00:00:00 EDT

Conditions: Mesotheliomas Pleural
Interventions: Biological: Mesopher
Sponsors: Erasmus Medical Center
Recruiting