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Asbestos Mesothelioma Cancer Clinical Trials

The US Government keeps an online database, at clinicaltrials.gov, of clinical research studies for Mesothelioma cancer, but doesn't review or approve the safety and science of these trials. The website is maintained by the National Library of Medicine (NLM). The links below go to the clinical trial information on clinicaltrials.gov. Talk with your health care professional about possible risks and benefits before joining any studies.

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

Tue, 24 Dec 2024 00:00:00 EST

Conditions: Mesothelioma; Malignant Mesothelioma (MM); Early-stage Mesothelioma; Subclinical Mesothelioma; BRCA1-Associated Protein-1 (BAP1) Mutations; Early-stage BAP1-associated Malignancies
Interventions: Drug: alrizomadlin
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

Tue, 24 Dec 2024 00:00:00 EST

Conditions: Malignant Mesothelioma; Metastatic Malignant Solid Tumor; Advanced Solid Tumor
Interventions: Drug: ISM6331
Sponsors: InSilico Medicine Hong Kong Limited
Recruiting

A Study of Sacituzumab Govitecan in People with Mesothelioma

Fri, 20 Dec 2024 00:00:00 EST

Conditions: Mesothelioma; Mesotheliomas Pleural; Mesothelioma; Pleura
Interventions: Drug: Sacituzumab govitecan-hziy
Sponsors: Memorial Sloan Kettering Cancer Center; Gilead Sciences
Recruiting

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

Thu, 12 Dec 2024 00:00:00 EST

Conditions: Solid Tumor
Interventions: Drug: ACTM-838
Sponsors: Actym Therapeutics, Inc.
Recruiting

Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study)

Wed, 18 Dec 2024 00:00:00 EST

Conditions: Pleural Mesothelioma
Interventions: Drug: Carboplatin/Cisplatin - Pemetrexed - Pembrolizumab
Sponsors: Istituto Oncologico Veneto IRCCS; MSD Italia S.r.l.
Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

Fri, 13 Dec 2024 00:00:00 EST

Conditions: Unresectable Pleural Mesothelioma
Interventions: Drug: Volrustomig; Drug: Pemetrexed; Drug: Carboplatin; Drug: Cisplatin; Drug: Nivolumab; Drug: Ipilimumab
Sponsors: AstraZeneca
Recruiting

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Fri, 20 Dec 2024 00:00:00 EST

Conditions: Locally Advanced Solid Tumor
Interventions: Drug: TNG462; Drug: Pembrolizumab
Sponsors: Tango Therapeutics, Inc.
Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Fri, 13 Dec 2024 00:00:00 EST

Conditions: Advanced Renal Cell Carcinoma; Advanced Mesothelioma; Advanced Osteosarcoma
Interventions: Drug: CAR.70/IL15-transduced CB-derived NK cells; Drug: Fludarabine phosphate; Drug: Cyclophosphamide
Sponsors: M.D. Anderson Cancer Center
Recruiting

Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma

Thu, 19 Dec 2024 00:00:00 EST

Conditions: Malignant Pleural Mesothelioma
Interventions: Radiation: Proton beam therapy
Sponsors: University College, London; Asthma + Lung UK; Mesothelioma UK; University of Sheffield
Recruiting

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Tue, 24 Dec 2024 00:00:00 EST

Conditions: Cancer; Solid Tumor; Solid Carcinoma; Advanced Cancer; DIPG Brain Tumor; Ovary Cancer; Breast Cancer; Papillary Thyroid Cancer; Head and Neck Cancer; Gastric Cancer; Nsclc; Mesotheliomas Pleural; Mesothelioma Peritoneum; Esophageal Cancer; Diffuse Midline Glioma, H3 K27M-Mutant; Endometrial Cancer; Cervical Cancer; Melanoma; Colorectal Cancer; Glioma, Malignant
Interventions: Drug: AMXT1501; Drug: DFMO
Sponsors: Aminex Therapeutics, Inc.
Terminated